DEEP DIVE.

INGREDIENT BREAKDOWN +

CHRG Immunity Amp integrates a cultivated Organic Cordyceps Sinensis species grown on oats. As the mushroom grows the food source slowly becomes part of the entire mushroom, called the Mycelium. It has been shown that there are major benefits in the Mycelium so we have included that part in the product. Always look for a mushroom product with Mycelium because you don’t want to miss out on all those added benefits.

Cordyceps belongs to the family of numerous mushrooms, which are parasitic organisms & grow on various insects and anthropods in the high plateaus of Nepal & Tibet. Historically, Cordyceps was used in ancient Asia exclusively in the Emperor’s palace because they were so rare. However, today they are cultivated on a large scale using oats & making them available to everyone. Cordyceps in was most commonly used for kidney disorders, for liver problems, increase sperm production, increase blood production, anti-depressant, persistent cough, excessive tiredness, anemia & impotence.

Today, they have discovered that Cordyceps have massive amounts of bioactive components. Some of these extracted components include Cordycepin, Ergosterol, Mannitol, Adenosine, Polysaccharide (also known as Beta-Glucan), Sterol, Nucleoside, Protein, Amino Acids, and Polypeptides. In the study below, these components had corresponding pharmacological actions shown to have anti-inflammatory, antioxidant, anti-tumor, anti-apoptosis and immunomodulatory actions.

It is difficult at this point to determine which parts or components of Cordyceps Sinensis are contributing to its positive effects on the human immune system. Further research and technological advances will eventually identify and isolate certain components for certain specific benefits. However, because the science has not yet reached this level of sophistication, we have added the complete species along with the Mycelium which, as discussed, has been shown to have benefits beyond the fruiting body alone.

PERFORMANCE BENEFITS +

CHRG® HARDER WITH CORDYCEPS Cordyceps Sinensis has also been recognized as an adaptogen, meaning that it can non-specifically enhance the human body. According to the primary definition of adaptogens, these substances must be non-specific and must assist the human body in resisting a wide range of adverse conditions, such as physical, chemical or biological stress. These stressors may include environmental contaminates, climate stressor, radiation, infectious diseases and emotional stress. These adaptogens must maintain homeostasis without disrupting normal body functions, that is, these substances can offset or resist physical ailments caused by external stress. If there is one thing extreme people should be putting in their body it should be a daily dose of Cordyceps Sinensis.

Cordyceps is believed to increase the body’s production of the energy molecule (ATP) Adenosine Triphosphate. ATP is responsible for delivering energy to all bodily cells from the lung to muscles. It is responsible for healthy function and biochemical pathways. The Cordyceps potential on ATP production may increase energy output throughout the day.

PROPER DOSAGE +

There is not a recommended amount we should be consuming. Research and benefits have been observed between 1-3 grams. CHRG Immunity Amp decided on 1.9 gram as the best option for amplifying this innate immune response.

SOURCES +

Xu YF. Effect of Polysaccharide from Cordyceps militaris (Ascomycetes) on Physical Fatigue Induced by Forced Swimming. Int J Med Mushrooms. 2016;18(12):1083-1092. Liao, L., He, Y., Li, L. et al. A preliminary review of studies on adaptogens: comparison of their bioactivity in TCM with that of ginseng-like herbs used worldwide. Chin Med 13, 57 (2018). Yi Liu, Jihui Wang, Wei Wang, Hanyue Zhang, Xuelan Zhang, and Chunchao Han. Medicinal Mushroom for Prevention of Disease of Modern Civilization. The Chemical Constituents and Pharmacological Actions of Cordyceps sinensis. 2015. 12 pages. Jia-Shi Zhu, Georges M. Halpern, and Kenneth Jones. The Journal of Alternative and Complementary Medicine.Oct 1998. 289-303. Shashidhar MG, Giridhar P, Udaya Sankar K, Manohar B. Bioactive principles from Cordyceps sinensis: A potent food supplement - A review. J Funct Foods. 2013;5(3):1013-1030. Yalin W., Cuirong S., Yuanjiang P. Studies on isolation and structural features of a polysaccharide from the mycelium of an Chinese edible fungus (Cordyceps sinensis) Carbohydrate Polymers. 2006;63:51–256. Yu H., Wang B., Huang S., Duh P. Comparison of protective effects between cultured Cordyceps militaris and natural Cordyceps sinensis against oxidative damage. Journal of Agricultural and Food Chemistry. 2006;54:3132–3138. Xiao JH, Xiao DM, Chen DX, Xiao Y, Liang ZQ, Zhong JJ. Polysaccharides from the Medicinal Mushroom Cordyceps taii Show Antioxidant and Immunoenhancing Activities in a D-Galactose-Induced Aging Mouse Model. Evid Based Complement Alternat Med. 2012. Vasiljevic JD, Zivkovic LP, Cabarkapa AM, Bajic VP, Djelic NJ, Spremo-Potparevic BM. Cordyceps sinensis: Genotoxic Potential in Human Peripheral Blood Cells and Antigenotoxic Properties Against Hydrogen Peroxide by Comet Assay. Altern Ther Health Med. 2016;22 Suppl 2:24-31. Yan XF, Zhang ZM, Yao HY, et al. Cardiovascular protection and antioxidant activity of the extracts from the mycelia of Cordyceps sinensis act partially via adenosine receptors. Phytother Res. 2013;27(11):1597-1604. Kuo YC, Tsai WJ, Shiao MS, Chen CF, Lin CY. Cordyceps sinensis as an immunomodulatory agent. Am J Chin Med. 1996;24(2):111-125. Park SY, Jung SJ, Ha KC, et al. Anti-inflammatory effects of Cordyceps mycelium (Paecilomyces hepiali, CBG-CS-2) in Raw264.7 murine macrophages. Orient Pharm Exp Med. 2015;15(1):7-12. doi:10.1007/s13596-014-0173-3.

INGREDIENT BREAKDOWN +

CHRG Immunity Amp contains a patent-protected yeast beta 1,3-D-glucan, also known as, beta-glucan. The multi-step process extracts the purist form of insoluble yeast beta-glucan, this is important because other extracts of beta-glucan can show large amounts of impurities you don’t really want in your immunity product. The beta-glucan found in Immudyne primes the innate immune response.

Working, similar to, Vitamin D’s immune activation, beta-glucan activates neutrophils, B-lymphocytes, T-helper cells, Natural Killer 1 cells, and macrophages sent to destroy pathogens. So, it works very similar to Vitamin D when looking at the overall amplification of the immune system, but it gets there following a different pathway. The advantage of beta glucan is that it can be taken orally and it is acid resistant so it passes through the stomach unchanged. In addition, the intestine lacks a specific enzyme that can break it down. Beta glucan can initiate immunity but does not over stimulate – the white blood cells in the immune system. This is important because we want to keep the immune system primed and ready to attack pathogens, and Immudyne beta-glucan does this.

Cordyceps also contains beta-glucan, not only from the mushroom itself but from the Mycelium. What impact do these have beyond immunity? Stay tuned, research is beginning to uncover the benefits of mushroom beta-glucans. If you’re counting, CHRG Immunity Amp contains three different types of beta-glucan all which have their benefits to the body.

PERFORMANCE BENEFITS +

CHRG® HARDER WITH BETA-GLUCAN Discussed or not, a top performance is dependent on many things. The body must be injury free, fully recovered, hydrated, fueled, mentally positive and free of sickness. Yes, many of us just go out and do our thing, but when we really think about it, so many things need to be in order, for us to perform optimally, and having a strong immune system is just as important as being injury free.

CHRG Immunity Amp has been scientifically researched and developed based on the components, of the formula, to all work in concert and thus amplifying the immune response these components could never do alone or with different sources of ingredients. We dug in deep and trialed ourselves, so we know you’ll see the difference in whatever you decide to charge in life.

PROPER DOSAGE +

The Beta-Glucan we have added to our CHRG Immunity Amp Daily Mix-In Powder is one of the purest forms available and because of this it has a very low dosage response at 30 mg each day. In the case of Beta-Glucan 1,3 – more is not necessarily better.

SOURCES +

Abdul Rohman, Irnawati, Yuny Erwanto, Endang Lukitaningsih, Muhamad Rafi, Nurrulhidayah A. Fadzilah, Anjar Windarsih, Ainin Sulaiman, Zalina Zakaria. (2019) Virgin Coconut Oil: Extraction, Physicochemical Properties, Biological Activities and Its Authentication Analysis. Food Reviews International 0:0, pages 1-21. Wallace TC. Health Effects of Coconut Oil-A Narrative Review of Current Evidence. J Am Coll Nutr. 2019;38(2):97-107. Joshi S, Kaushik V, Gode V, Mhaskar S. Coconut Oil and Immunity: What do we really know about it so far?. J Assoc Physicians India. 2020;68(7):67-72. Enig MG. Health and nutritional benefits from coconut oil: an important functional food for the 21st century. AVOC Lauric Oils Symposium, Ho Chi Min City, Vietnam. 1996; 25. Kappally S, Shirwaikar A, Shirwaikar A. Coconut oil–a review of potential applications. Hygeia Journal of Drugs and Medicine 2015; 7.2:34-41. Kabara J. Pharmacological effects of coconut oil vs. monoglycerides-The effects of preformed sn1,(3)-monolaurin and coconut oil are set forth. Inform-International News on Fats Oils and Related Materials 2005; 16.6:386-387.

INGREDIENT BREAKDOWN +

CHRG Immunity Amp contains excellent amounts of Zinc Gluconate. It is a dietary essential mineral, therefore, humans must regularly get Zinc into their diet. It's the third most deficient micro-nutrient in the American diet and especially in the elderly.

Zinc participates in numerous biological functions, including some 300 enzymes, and was first discovered to be of prime importance in growth and development. Today, it's now understood to be the most important trace mineral for proper immune function, including cell health to facilitate oxygen transport and storage, and zinc can also assist several antioxidant enzymatic reactions.

It is estimated that nearly 2 billion people worldwide are deficient in Zinc, and inadequate levels can limit an individual’s ability to provide an adequate immune response to infections as well as creating other imbalances in body function.

One important study is a multiple, meta-analyses and pooled analyses of randomized controlled trials which have shown that oral Zinc supplementation reduces the incidence rate of acute respiratory infections by 35%, and a shortened duration of flu-like symptoms by approximately 2 days, and improved rate of recovery. Zinc’s absorption is increased by getting adequate supply of Vitamin D.

PERFORMANCE BENEFITS +

CHRG® HARDER WITH ZINC Because hard working bodies can create zinc deficiencies, it's important to be taking in zinc to help heal injuries and muscle damage. However, too much can also create other mineral deficiencies, so stick to the 11 mg found in CHRG Immunity Amp.

PROPER DOSAGE +

As with many vitamins and mineral involved in the immune function the problems arise when adequate intake is not achieved. This inadequate intake sets the body up for a poor response to pathogens, bacteria and viruses which then determines the outcome on the body and cells. If we take into consideration the population which is most susceptible to COVID-19, it is apparent that poor nutrient status of Zinc and Vitamin D can only make matters worse.

So, it is necessary and important to keep those surging through the body on a daily basis. The Daily Recommmended Value for Zinc is an adequate amount to take on a daily basis, taking more than the DRV can create other issues, so we have kept it at an optimal amount of 11 mg per daily serving.

SOURCES +

Read SA, Obeid S, Ahlenstiel C, Ahlenstiel G. The role of zinc in antiviral immunity. Advances in Nutrition. 2019 Jul 1;10(4):696-710. Hemilä H, Fitzgerald JT, Petrus EJ, Prasad A. Zinc acetate lozenges may improve the recovery rate of common cold patients: an individual patient data meta-analysis. In Open forum infectious diseases 2017 (Vol. 4, No. 2, p. ofx059). US: Oxford University Press. Roth DE, Richard SA, Black RE. Zinc supplementation for the prevention of acute lower respiratory infection in children in developing countries: meta-analysis and meta-regression of randomized trials. International journal of epidemiology. 2010 Jun 1;39(3):795-808. Mocchegiani, et al. Zinc: Dietary Intake and Impact of Supplementation on Immune Function in the Elderly. Age. 2013, Jun; 35(3):839-60. Simin N Meydani, Junaidah B Barnett, Gerard E Dallal, Basil C Fine, Paul F Jacques, Lynette S Leka, Davidson H Hamer. The American Journal of Clinical Nutrition, Volume 86, Issue 4, October 2007, Pages 1167–1173. Hemilä H, Fitzgerald JT, Petrus EJ, Prasad A. Zinc Acetate Lozenges May Improve the Recovery Rate of Common Cold Patients: An Individual Patient Data Meta-Analysis. Open Forum Infect Dis. 2017;4(2):ofx059. Published 2017 Apr 3. te Velthuis AJ, van den Worm SH, Sims AC, Baric RS, Snijder EJ, van Hemert MJ. Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture. PLoS Pathog. 2010;6(11):e1001176. Published 2010 Nov 4. McDonald R, Keen CL. Iron, zinc and magnesium nutrition and athletic performance. Sports Med. 1988;5(3):171-184.

INGREDIENT BREAKDOWN +

CHRG Immunity Amp uses one of the only vegan sourced and sustainable Vitamin D3 available. This product is only derived from sustainable algae. Vitamin D3, known as Cholecalciferol, is the most bioavailable source of Vitamin D for the human body, in fact, the Vitamin D we synthesized is from the sun.

For years, it has been known, studied, and proven that Vitamin D benefits our bones and muscles. However, recent research and a global epidemic has brought Vitamin D deficiency and its impact on the immune system to the forefront. It’s one of the 24 micronutrients critical to human survival and every single cell in the body has a receptor for Vitamin D. The most studied and proven benefits from Vitamin D are support for bones, teeth, brain, nervous system, as well as regulating insulin and blood sugar levels. It supports the health of the immune system, lung function and cardiovascular health.

Everybody needs Vitamin D for normal function and growth of the body. A deficiency can create many issues. Globally, over 1 billion people are deficient in Vitamin D because they don’t get enough sunshine, eat poorly due to lack of access to nutritious food or they have underlying health problems. Studies show that Vitamin D lowers the risk of contracting infections in the lungs, including those from viruses and bacteria. It speeds up the immune cell response to infections by greatly minimizing pathogenic spread into healthy cells. Zinc absorption is enhanced by Vitamin D, too, and this helps activate T cells, from the thymus, which attach and destroy viruses before they can replicate.

PERFORMANCE BENEFITS +

CHRG® HARDER WITH VITAMIN D3 We know Vitamin D is a key player in bone health, immunity and inflammatory response. It also may potentially be necessary for peak muscle function, muscle force and muscle velocity resulting in greater performance in athletes and adventurers alike. While this specific area of study is somewhat in its infancy relative to other applications, insights into the importance of Vitamin D correlating to performance will continue to grow.

PROPER DOSAGE +

Vitamin D, is a fat soluble vitamin and can be stored in the body, so very large doses can cause issues if continually ingested. The NIH warns that consuming over 100 mcg daily can potentially be toxic if taken for long periods of time. We’ve included a safe and steady amount of 56 mcg in our CHRG Immunity Amp Daily Mix-In Powder.

SOURCES +

Adrian R Martineau, David A Jolliffe, Richard L Hooper, Lauren Greenberg, John F Aloia, Peter Bergman, Gal Dubnov-Raz, Susanna Esposito, Davaasambuu Ganmaa, Adit A Ginde, Emma C Goodall, Cameron C Grant, Christopher J Griffiths, Wim Janssens, Ilkka Laaksi, Semira Manaseki-Holland, David Mauger, David R Murdoch, Rachel Neale, Judy R Rees, Steve Simpson, Iwona Stelmach, Geeta Trilok Kumar, Mitsuyoshi Urashima, Carlos A Camargo. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. BMJ, 2017. Martineau AR, Jolliffe DA, Hooper RL, et al. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. BMJ. 2017;356:i6583. Published 2017 Feb 15. Ali Daneshkhah, Vasundhara Agrawal, Adam Eshein, Hariharan Subramanian, Hemant Kumar Roy, Vadim Backman. The Possible Role of Vitamin D in Suppressing Cytokine Storm and Associated Mortality in COVID-19 Patients. medRxiv, Posted April 30, 2020. Vitamin D: Fact Sheet for Health Professionals. National Institutes of Health. https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/. Accessed Sept. 29, 2017. Vitamin D: Fact Sheet for Consumers. National Institutes of Health. https://ods.od.nih.gov/factsheets/VitaminD-Consumer/. Accessed Sept. 29, 2017. Cannell JJ, Hollis BW, Sorenson MB, Taft TN, Anderson JJ. Athletic performance and Vitamin D. Med. Sci. Sports Exerc. 2009; 41:1102-10.